Matrix Metalloproteinases Limit Functional Recovery after Spinal Cord Injury by Modulation of Early Vascular Events

Inflammation in general and proteinases generated as a result are likely mediators of early secondary pathogenesis after spinal cord injury. We report that matrix metalloproteinase-9 (MMP-9) plays an important role in blood–spinal cord barrier dysfunction, inflammation, and locomotor recovery. MMP-9...

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Hauptverfasser: Noble, Linda J., Donovan, Frances, Igarashi, Takuji, Goussev, Staci, Werb, Zena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2002
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ARTICLE
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792199/
https://ncbi.nlm.nih.gov/pubmed/12196576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-17-07526.2002
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