Predictable dynamic program of timing of DNA replication in human cells

The organization of mammalian DNA replication is poorly understood. We have produced high-resolution dynamic maps of the timing of replication in human erythroid, mesenchymal, and embryonic stem (ES) cells using TimEX, a method that relies on gaussian convolution of massive, highly redundant determi...

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Bibliografske podrobnosti
Main Authors: Desprat, Romain, Thierry-Mieg, Danielle, Lailler, Nathalie, Lajugie, Julien, Schildkraut, Carl, Thierry-Mieg, Jean, Bouhassira, Eric E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Methods
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792175/
https://ncbi.nlm.nih.gov/pubmed/19767418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.094060.109
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