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Influence of Temporary Chondroitinase ABC-Induced Glycosaminoglycan Suppression on Maturation of Tissue-Engineered Cartilage

OBJECTIVE: A fundamental challenge of cartilage tissue engineering has been the inability to promote collagen synthesis up to native levels. In contrast, recent protocols have demonstrated that glycosaminoglycans (GAG) can be synthesized to native levels in 4–6 weeks of in vitro culture. We hypothes...

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Autores principales: Bian, Liming, Crivello, Keith M., Ng, Kenneth W., Xu, Duo, Williams, David Y., Ateshian, Gerard A., Hung, Clark T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792113/
https://ncbi.nlm.nih.gov/pubmed/19196151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2008.0495
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