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Combined Effects of Scaffold Stiffening and Mechanical Preconditioning Cycles on Construct Biomechanics, Gene Expression, and Tendon Repair Biomechanics

Our group has previously reported that in vitro mechanical stimulation of tissue-engineered tendon constructs significantly increases both construct stiffness and the biomechanical properties of the repair tissue after surgery. When optimized using response surface methodology, our results indicate...

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Bibliographic Details
Main Authors: Nirmalanandhan, Victor Sanjit, Juncosa-Melvin, Natalia, Shearn, Jason T., Boivin, Gregory P., Galloway, Marc T., Gooch, Cynthia, Bradica, Gino, Butler, David L.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792106/
https://ncbi.nlm.nih.gov/pubmed/19191501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2008.0335
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