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Three-Dimensional In Vitro Effects of Compression and Time in Culture on Aggregate Modulus and on Gene Expression and Protein Content of Collagen Type II in Murine Chondrocytes

The objectives of this study were to determine how culture time and dynamic compression, applied to murine chondrocyte–agarose constructs, influence construct stiffness, expression of col2 and type II collagen. Chondrocytes were harvested from the ribs of six newborn double transgenic mice carrying...

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Detalhes bibliográficos
Main Authors: Chokalingam, Kumar, Hunter, Shawn, Gooch, Cynthia, Frede, Chris, Florer, Jane, Wenstrup, Richard, Butler, David
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792064/
https://ncbi.nlm.nih.gov/pubmed/19231914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2008.0560
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