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Modelling the occurrence and severity of enoxaparin-induced bleeding and bruising events

AIMS: To develop a population pharmacokinetic–pharmacodynamic model to describe the occurrence and severity of bleeding or bruising as a function of enoxaparin exposure. METHODS: Data were obtained from a randomized controlled trial (n = 118) that compared conventional dosing of enoxaparin (product...

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Detalhes bibliográficos
Main Authors: Barras, Michael A, Duffull, Stephen B, Atherton, John J, Green, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791976/
https://ncbi.nlm.nih.gov/pubmed/19916994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03518.x
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