TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

BACKGROUND: Acquired somatic deletions and loss-of-function mutations in one or several codons of the TET2 (Ten-Eleven Translocation-2) gene were recently identified in hematopoietic cells from patients with myeloid malignancies, including myeloproliferative disorders and myelodys-plastic syndromes....

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Autors principals: Kosmider, Olivier, Gelsi-Boyer, Véronique, Ciudad, Marion, Racoeur, Cindy, Jooste, Valérie, Vey, Norbert, Quesnel, Bruno, Fenaux, Pierre, Bastie, Jean-Noël, Beyne-Rauzy, Odile, Stamatoulas, Aspasia, Dreyfus, François, Ifrah, Norbert, de Botton, Stéphane, Vainchenker, William, Bernard, Oliver A., Birnbaum, Daniel, Fontenay, Michaëla, Solary, Eric
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791942/
https://ncbi.nlm.nih.gov/pubmed/19797729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011205
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