Cystic Fibrosis-Related Diabetes: From CFTR Dysfunction to Oxidative Stress

Cystic fibrosis (CF) represents the most common lethal autosomal recessive disorder in the Caucasian population. It is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, resulting in abnormal Na(+) and Cl(−) transport in several tissues. Its main clinical manifestations i...

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Detalhes bibliográficos
Main Authors: Ntimbane, Thierry, Comte, Blandine, Mailhot, Geneviève, Berthiaume, Yves, Poitout, Vincent, Prentki, Marc, Rabasa-Lhoret, Rémi, Levy, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: The Australian Association of Clinical Biochemists 2009
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791770/
https://ncbi.nlm.nih.gov/pubmed/20011209
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