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Glycogen synthase kinase-3/Shaggy mediates ethanol-induced excitotoxic cell death of Drosophila olfactory neurons

It has long been known that heavy alcohol consumption leads to neuropathology and neuronal death. While the response of neurons to an ethanol insult is strongly influenced by genetic background, the underlying mechanisms are poorly understood. Here, we show that even a single intoxicating exposure t...

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Bibliographic Details
Main Authors: French, Rachael L., Heberlein, Ulrike
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791575/
https://ncbi.nlm.nih.gov/pubmed/19923438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910813106
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