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Glycogen synthase kinase-3/Shaggy mediates ethanol-induced excitotoxic cell death of Drosophila olfactory neurons

It has long been known that heavy alcohol consumption leads to neuropathology and neuronal death. While the response of neurons to an ethanol insult is strongly influenced by genetic background, the underlying mechanisms are poorly understood. Here, we show that even a single intoxicating exposure t...

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Detalhes bibliográficos
Main Authors: French, Rachael L., Heberlein, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791575/
https://ncbi.nlm.nih.gov/pubmed/19923438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910813106
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