Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

Microbial nucleic acids are critical for the induction of innate immune responses, a host defense mechanism against infection by microbes. Recent studies have indicated that double-stranded DNA (dsDNA) induces potent innate immune responses via the induction of type I IFN (IFN) and IFN-inducible gen...

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Hlavní autoři: Saitoh, Tatsuya, Fujita, Naonobu, Hayashi, Takuya, Takahara, Keigo, Satoh, Takashi, Lee, Hanna, Matsunaga, Kohichi, Kageyama, Shun, Omori, Hiroko, Noda, Takeshi, Yamamoto, Naoki, Kawai, Taro, Ishii, Ken, Takeuchi, Osamu, Yoshimori, Tamotsu, Akira, Shizuo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791563/
https://ncbi.nlm.nih.gov/pubmed/19926846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911267106
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