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The effects of clonidine on discrete-trial delayed spatial alternation in two rat models of memory loss

Spatial memory impairments observed in Alzheimer’s disease and schizophrenia have been attributed to many factors, including glutamate hypofunction and reduced hippocampal volume. Clonidine, a non-specific α(2) adrenergic receptor agonist, improves spatial memory in animals treated with the N-methyl...

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Detalhes bibliográficos
Main Authors: Bardgett, Mark E., Points, Megan, Ramsey-Faulkner, Christian, Topmiller, Jeff, Roflow, John, McDaniel, Travis, Lamontagne, Timberly, Griffith, Molly S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791505/
https://ncbi.nlm.nih.gov/pubmed/17882233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301580
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