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Caspase-1 inhibitor Prevents Neurogenic Pulmonary Edema after Subarachnoid Hemorrhage in Mice

BACKGROUND AND PURPOSE: We examined the effects of a caspase-1 inhibitor, N-Ac-Tyr-Val-Ala-Asp-chloromethyl ketone (Ac-YVAD-CMK), on neurogenic pulmonary edema (NPE) in the endovascular perforation model of subarachnoid hemorrhage (SAH) in mice. METHODS: Ninety-seven mice were assigned to sham, SAH+...

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Detalhes bibliográficos
Main Authors: Suzuki, Hidenori, Sozen, Takumi, Hasegawa, Yu, Chen, Wanqiu, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791454/
https://ncbi.nlm.nih.gov/pubmed/19875734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.566109
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