A Novel Phase Variation Mechanism in the Meningococcus Driven by a Ligand-Responsive Repressor and Differential Spacing of Distal Promoter Elements

Phase variable expression, mediated by high frequency reversible changes in the length of simple sequence repeats, facilitates adaptation of bacterial populations to changing environments and is frequently important in bacterial virulence. Here we elucidate a novel phase variable mechanism for NadA,...

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Bibliografische gegevens
Hoofdauteurs: Metruccio, Matteo M. E., Pigozzi, Eva, Roncarati, Davide, Berlanda Scorza, Francesco, Norais, Nathalie, Hill, Stuart A., Scarlato, Vincenzo, Delany, Isabel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791445/
https://ncbi.nlm.nih.gov/pubmed/20041170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000710
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