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Non-homeodomain regions of Hox proteins mediate activation versus repression of Six2 via a single enhancer site in vivo

Hox genes control many developmental events along the AP axis, but few target genes have been identified. Whether target genes are activated or repressed, what enhancer elements are required for regulation, and how different domains of the Hox proteins contribute to regulatory specificity is poorly...

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Main Authors: Yallowitz, Alisha R., Gong, Ke-Qin, Swinehart, Ilea T., Nelson, Lisa T., Wellik, Deneen M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791332/
https://ncbi.nlm.nih.gov/pubmed/19716816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.08.020
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