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Zinc-dependent dimers observed in crystals of human endostatin

The crystal structure of human endostatin reveals a zinc-binding site. Atomic absorption spectroscopy indicates that zinc is a constituent of both human and murine endostatin in solution. The human endostatin zinc site is formed by three histidines at the N terminus, residues 1, 3, and, 11, and an a...

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Main Authors: Ding, Yuan-Hua, Javaherian, Kashi, Lo, Kin-Ming, Chopra, Rajiv, Boehm, Thomas, Lanciotti, Julia, Harris, B. A., Li, Yue, Shapiro, Robert, Hohenester, Erhard, Timpl, Rupert, Folkman, Judah, Wiley, Don C.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC27913/
https://ncbi.nlm.nih.gov/pubmed/9724722
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