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Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice

Drusen, the white yellowish deposits that can be seen in funduscopy, are a hallmark of age related macular disease (AMD). Histologically, drusen are believed to be dome-shaped or more confluent lipid accumulations between the retinal pigment epithelium and the choroicapillaries. Recent advances in m...

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Detalhes bibliográficos
Main Authors: Raoul, William, Feumi, Charles, Keller, Nicole, Lavalette, Sophie, Houssier, Marianne, Behar-Cohen, Francine, Combadière, Christophe, Sennlaub, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Karger Publishers 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791110/
https://ncbi.nlm.nih.gov/pubmed/18421223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000119860
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