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Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1
AIMS: A reduction in the level of thioredoxin 1 (Trx1) has been proposed as a possible mechanism for the tumor-specific growth arrest caused by inhibition of histone deacetylases (HDACs). In this study, we investigated the effect of trichostatin A (TSA), a potent HDAC inhibitor, on the proliferation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791053/ https://ncbi.nlm.nih.gov/pubmed/19633316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp263 |
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