Sensing Domain Dynamics in Protein Kinase A-Iα Complexes by Solution X-ray Scattering

The catalytic (C) and regulatory (R) subunits of protein kinase A are exceptionally dynamic proteins. Interactions between the R- and C-subunits are regulated by cAMP binding to the two cyclic nucleotide-binding domains in the R-subunit. Mammalian cells express four different isoforms of the R-subun...

Full description

Saved in:
Bibliographic Details
Main Authors: Cheng, Cecilia Y., Yang, Jie, Taylor, Susan S., Blumenthal, Donald K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791020/
https://ncbi.nlm.nih.gov/pubmed/19837668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059493
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items