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Transcriptional Activation of hTERT, the Human Telomerase Reverse Transcriptase, by Nuclear Factor of Activated T Cells

Telomerase is essential for telomere maintenance, and its activation is thought to be a critical step in cellular immortalization and tumorigenesis. Human telomerase reverse transcriptase (hTERT) is a major component of telomerase activity. We show here that hTERT is expressed soon after lymphocyte...

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Библиографические подробности
Главные авторы: Chebel, Amel, Rouault, Jean-Pierre, Urbanowicz, Iwona, Baseggio, Lucile, Chien, Wei-Wen, Salles, Gilles, Ffrench, Martine
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791003/
https://ncbi.nlm.nih.gov/pubmed/19843528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009183
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