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Demonstration of all-or-none loss of imprinting in mRNA expression in single cells
Loss of imprinting (LOI) is the reactivation of the silenced allele of an imprinted gene, leading to perturbation of monoallelic expression. We tested the hypothesis that LOI of PLAGL1, a representative maternally imprinted gene, occurs through an all-or-none process leading to a mixture of fully im...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790885/ https://ncbi.nlm.nih.gov/pubmed/19767614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp749 |
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