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Stretched Extracellular Matrix Proteins Turn Fouling and Are Functionally Rescued by the Chaperones Albumin and Casein

[Image: see text] While evidence is mounting that cells exploit protein unfolding for mechanochemical signal conversion (mechanotransduction), what mechanisms are in place to deal with the unwanted consequences of exposing hydrophobic residues upon force-induced protein unfolding? Here, we show that...

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Autors principals: Little, William C., Schwartlander, Ruth, Smith, Michael L., Gourdon, Delphine, Vogel, Viola
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2009
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790870/
https://ncbi.nlm.nih.gov/pubmed/19743815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl902365z
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