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Use of Excised Human Skin to Assess the Bioequivalence of Topical Products

BACKGROUND: Establishing the bioequivalence of topical drug products is a costly and time-consuming process since, with few exceptions, clinical efficacy trials are required. OBJECTIVE: To develop a surrogate for clinical bioequivalence testing through evaluation of the kinetics of drug absorption i...

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Detalhes bibliográficos
Main Authors: Franz, T.J., Lehman, P.A., Raney, S.G.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790798/
https://ncbi.nlm.nih.gov/pubmed/19707043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000235828
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