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When Is Standard Treatment Sufficiently Active to Make Use of a Placebo-Controlled Trial Unethical?

Research has demonstrated that double blinding can lessen the potential for bias in study outcomes, such as perceiving a drug as more effective in the experimental arm of a study. Effective double-blinding techniques minimize the influence of investigator and patient expectations.

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Detalhes bibliográficos
Main Authors: Grünwald, Hans W., Storm, Courtney D., Jacobson, Geraldine M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790645/
https://ncbi.nlm.nih.gov/pubmed/20856725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JOP.0922503
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