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Efficient Assembly and Secretion of Recombinant Subviral Particles of the Four Dengue Serotypes Using Native prM and E Proteins

BACKGROUND: Flavivirus infected cells produce infectious virions and subviral particles, both of which are formed by the assembly of prM and E envelope proteins and are believed to undergo the same maturation process. Dengue recombinant subviral particles have been produced in cell cultures with eit...

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Autors principals: Wang, Pei-Gang, Kudelko, Mateusz, Lo, Joanne, Siu, Lewis Yu Lam, Kwok, Kevin Tsz Hin, Sachse, Martin, Nicholls, John M., Bruzzone, Roberto, Altmeyer, Ralf M., Nal, Béatrice
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790604/
https://ncbi.nlm.nih.gov/pubmed/20016834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008325
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