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Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links
Human DNA polymerase N (PolN) is an A-family nuclear DNA polymerase whose function is unknown. This study examines the possible role of PolN in DNA repair in human cells treated with PolN-targeted siRNA. HeLa cells with siRNA-mediated knockdown of PolN were more sensitive than control cells to DNA c...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790558/ https://ncbi.nlm.nih.gov/pubmed/19908865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015346 |
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