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The Mitochondrial Permeability Transition Pore: A Molecular Target for Amyotrophic Lateral Sclerosis Therapy
Effective therapies are needed for the treatment of amyotrophic lateral sclerosis (ALS), a fatal type of motor neuron disease. Morphological, biochemical, molecular genetic, and cell/animal model studies suggest that mitochondria have potentially diverse roles in neurodegenerative disease mechanisms...
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Natura: | Artigo |
Lingua: | Inglês |
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2009
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790555/ https://ncbi.nlm.nih.gov/pubmed/19651206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.07.009 |
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