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Cochlear Implants Stimulate Activity-Dependent CREB Pathway in the Deaf Auditory Cortex: Implications for Molecular Plasticity Induced by Neural Prosthetic Devices

Neural activity modulates the maturation of synapses and their organization into functional circuits by regulating activity-dependent signaling pathways. Phosphorylation of cyclic AMP/Ca(2+)-responsive element-binding protein (CREB) is widely accepted as a stimulus-inducible event driven by calcium...

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Detalhes bibliográficos
Main Authors: Tan, Justin, Widjaja, Sandra, Xu, Jin, Shepherd, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790391/
https://ncbi.nlm.nih.gov/pubmed/18063565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhm206
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