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Role of the Ubiquitin Proteasome System in Regulating Skin Pigmentation

Pigmentation of the skin, hair and eyes is regulated by tyrosinase, the critical rate-limiting enzyme in melanin synthesis by melanocytes. Tyrosinase is degraded endogenously, at least in part, by the ubiquitin proteasome system (UPS). Several types of inherited hypopigmentary diseases, such as ocul...

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Detalhes bibliográficos
Main Authors: Ando, Hideya, Ichihashi, Masamitsu, Hearing, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790116/
https://ncbi.nlm.nih.gov/pubmed/20057953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10104428
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