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Chemical and Genetic Wrappers for Improved Phage and RNA Display
An Achilles heel inherent to all molecular display formats, background binding between target and display system introduces false positives into screens and selections. For example, the negatively charged surfaces of phage, mRNA, and ribosome display systems bind with unacceptably high non-specifici...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790074/ https://ncbi.nlm.nih.gov/pubmed/18973165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800366 |
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