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Antagonism of the Antinociceptive Effect of Nitrous Oxide by Inhibition of Enzyme Activity or Expression of Neuronal Nitric Oxide Synthase in the Mouse Brain and Spinal Cord
Previous studies have implicated nitric oxide (NO) in the antinociceptive response to the anesthetic gas nitrous oxide (N(2)O). The present study was conducted to confirm this NO involvement using pharmacological and gene knockdown and knockout strategies to inhibit the supraspinal and spinal produc...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790018/ https://ncbi.nlm.nih.gov/pubmed/19818753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.09.059 |
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