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Local delivery of a collagen binding FGF-1 chimera to smooth muscle cells in collagen scaffolds for vascular tissue engineering

We investigated the delivery of R136K-CBD (a collagen binding mutuat chimera of fibroblast growth factor-1) with a type I collagen scaffold as the delivery vehicle to smooth muscle cells (SMCs) for vascular tissue engineering. The binding affinity of R136K-CBD to 3-D collagen scaffolds was investiga...

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Autors principals: Pang, Yonggang, Wang, Xiaoli, Ucuzian, Areck A., Brey, Eric M., Burgess, Wilson H., Jones, Kathryn J., Alexander, Thomas D., Greisler, Howard P.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789982/
https://ncbi.nlm.nih.gov/pubmed/19853908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.10.007
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