Genetical Toxicogenomics in Drosophila Identifies Master Modulatory Loci that are Regulated by Developmental Exposure to Lead

The genetics of gene expression in recombinant inbred lines (RILs) can be mapped as expression quantitative trait loci (eQTLs). So-called “genetical genomics” studies have identified locally-acting eQTLs (cis-eQTLs) for genes that show differences in steady state RNA levels. These studies have also...

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Detalhes bibliográficos
Main Authors: Ruden, Douglas M., Chen, Lang, Possidente, Debra, Possidente, Bernard, Rasouli, Parsa, Wang, Luan, Lu, Xiangyi, Garfinkel, Mark D., Hirsch, Helmut V. B., Page, Grier P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789871/
https://ncbi.nlm.nih.gov/pubmed/19737576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2009.08.011
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