Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions

Apolipoprotein (apo) C-III plays a regulatory role in VLDL lipolysis and clearance. In this study, we determined a potential intracellular role of apoC-III in hepatic VLDL assembly and secretion. Stable expression of recombinant apoC-III in McA-RH7777 cells resulted in increased secretion efficiency...

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Main Authors: Sundaram, Meenakshi, Zhong, Shumei, Khalil, Maroun Bou, Links, Philip H., Zhao, Yang, Iqbal, Jahangir, Hussain, M. Mahmood, Parks, Robin J., Wang, Yuwei, Yao, Zemin
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789775/
https://ncbi.nlm.nih.gov/pubmed/19622837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900346-JLR200
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