Syk Tyrosine Kinase Acts as a Pancreatic Adenocarcinoma Tumor Suppressor by Regulating Cellular Growth and Invasion

We have identified the nonreceptor tyrosine kinase syk as a marker of differentiation/tumor suppressor in pancreatic ductal adenocarcinoma (PDAC). Syk expression is lost in poorly differentiated PDAC cells in vitro and in situ, and stable reexpression of syk in endogenously syk-negative Panc1 (Panc1...

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Detalhes bibliográficos
Main Authors: Layton, Tracy, Stalens, Cristel, Gunderson, Felizza, Goodison, Steve, Silletti, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789622/
https://ncbi.nlm.nih.gov/pubmed/19893036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090543
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