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Signal Regulatory Protein-β1 : A Microglial Modulator of Phagocytosis in Alzheimer’s Disease

The signal regulatory protein-β1 (SIRPβ1) is a DAP12-associated transmembrane receptor expressed in a subset of hematopoietic cells. Recently, it was shown that peritoneal macrophages express SIRPβ1, which positively regulated phagocytosis. Here, we found that SIRPβ1 was up-regulated and acted as a...

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Detalhes bibliográficos
Main Authors: Gaikwad, Sadanand, Larionov, Sergey, Wang, Yiner, Dannenberg, Holger, Matozaki, Takashi, Monsonego, Alon, Thal, Dietmar R., Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789620/
https://ncbi.nlm.nih.gov/pubmed/19893026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090147
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