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Preparation of Monodisperse Biodegradable Polymer Microparticles Using a Microfluidic Flow-focusing Device for Controlled Drug Delivery

Degradable microparticles have broad utility as vehicles for drug delivery and form the basis of several FDA-approved therapies. Conventional emulsion-based methods of manufacturing produce particles with a wide range of diameters (and thus kinetics of release) in each batch. This paper describes th...

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Detalhes bibliográficos
Main Authors: Xu, Qiaobing, Hashimoto, Michinao, Dang, Tram T., Hoare, Todd, Kohane, Daniel S., Whitesides, George M., Langer, Robert, Anderson, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789598/
https://ncbi.nlm.nih.gov/pubmed/19296563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.200801855
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