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Inhibition of the adenosine (2A) receptor-epoxyeicosatrienoic acid pathway renders Dahl salt-resistant rats hypertensive

Adenosine-induced renovasodilation in Dahl rats is mediated via activation of adenosine (2A) receptors (A(2A)R) and stimulation of epoxyeicosatrienoic acid (EET) synthesis. Unlike Dahl salt-resistant (SR) rats, salt-sensitive rats exhibit an inability to upregulate the A(2A)R-EET pathway with salt-l...

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Hlavní autoři: Liclican, Elvira L., Doumad, Anabel B., Wang, Jianjin, Li, Jing, Falck, John R., Stier, Charles T., Carroll, Mairéad A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789559/
https://ncbi.nlm.nih.gov/pubmed/19822802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.123570
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