Kisspeptin Signalling in the Hypothalamic Arcuate Nucleus Regulates GnRH Pulse Generator Frequency in the Rat

BACKGROUND: Kisspeptin and its G protein-coupled receptor (GPR) 54 are essential for activation of the hypothalamo-pituitary-gonadal axis. In the rat, the kisspeptin neurons critical for gonadotropin secretion are located in the hypothalamic arcuate (ARC) and anteroventral periventricular (AVPV) nuc...

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Main Authors: Li, Xiao-Feng, Kinsey-Jones, James S., Cheng, Yewsong, Knox, Alice M. I., Lin, Yuanshao, Petrou, Nikoletta A., Roseweir, Antonia, Lightman, Stafford L., Milligan, Stuart R., Millar, Robert P., O'Byrne, Kevin T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789414/
https://ncbi.nlm.nih.gov/pubmed/20016824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008334
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