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Implications of the Cancer Stem-Cell Hypothesis for Breast Cancer Prevention and Therapy

Recent research in breast biology has provided support for the cancer stem-cell hypothesis. Two important components of this hypothesis are that tumors originate in mammary stem or progenitor cells as a result of dysregulation of the normally tightly regulated process of self-renewal. As a result, t...

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Autori principali: Kakarala, Madhuri, Wicha, Max S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789399/
https://ncbi.nlm.nih.gov/pubmed/18539959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.3931
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