Neural Stem Cells as a Novel Platform for Tumor-Specific Delivery of Therapeutic Antibodies

BACKGROUND: Recombinant monoclonal antibodies have emerged as important tools for cancer therapy. Despite the promise shown by antibody-based therapies, the large molecular size of antibodies limits their ability to efficiently penetrate solid tumors and precludes efficient crossing of the blood-bra...

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Bibliographic Details
Main Authors: Frank, Richard T., Edmiston, Marissa, Kendall, Stephen E., Najbauer, Joseph, Cheung, Chia-Wei, Kassa, Thewodros, Metz, Marianne Z., Kim, Seung U., Glackin, Carlotta A., Wu, Anna M., Yazaki, Paul J., Aboody, Karen S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789379/
https://ncbi.nlm.nih.gov/pubmed/20016813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008314
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