The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene

Neuregulin-1 (NRG1) is both a candidate oncogene and candidate tumour suppressor gene. It encodes the heregulins and other mitogenic ligands for the ERBB family, but it also causes apoptosis in NRG1-expressing cells. We found that most breast cancer cell lines had reduced or undetectable expression...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chua, YL, Ito, Y, Pole, JCM, Newman, S, Chin, S-F, Stein, RC, Ellis, IO, Caldas, C, O’Hare, MJ, Murrell, A, Edwards, PAW
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789334/
https://ncbi.nlm.nih.gov/pubmed/19802002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.259
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados