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Bistability of Mitochondrial Respiration Underlies Paradoxical Reactive Oxygen Species Generation Induced by Anoxia

Increased production of reactive oxygen species (ROS) in mitochondria underlies major systemic diseases, and this clinical problem stimulates a great scientific interest in the mechanism of ROS generation. However, the mechanism of hypoxia-induced change in ROS production is not fully understood. To...

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Main Authors: Selivanov, Vitaly A., Votyakova, Tatyana V., Zeak, Jennifer A., Trucco, Massimo, Roca, Josep, Cascante, Marta
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789320/
https://ncbi.nlm.nih.gov/pubmed/20041200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000619
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