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A Randomized Clinical Trial Investigating the Relationship Between Aprotinin and Hypercoagulability in Off-Pump Coronary Surgery

BACKGROUND: Off-pump coronary artery bypass (OPCAB) surgery is associated with a hypercoagulable state in which the platelet thrombin receptor, protease-activated receptor-1 (PAR-1), helps propagate a thrombin burst within saphenous vein grafts. Aprotinin, used in cardiothoracic surgery mainly for i...

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Detalhes bibliográficos
Main Authors: Desai, Pranjal H., Kurian, Dinesh, Thirumavalavan, Nannan, Desai, Sneha P., Ziu, Pluen, Grant, Michael, White, Charles, Landis, R. Clive, Poston, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789288/
https://ncbi.nlm.nih.gov/pubmed/19843776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3181b81068
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