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Hypoxia regulates Insulin Receptor Substrate-2 expression to promote breast carcinoma cell survival and invasion
Insulin Receptor Substrate-2 (IRS-2) belongs to the IRS family of adaptor proteins that function as signaling intermediates for growth factor, cytokine and integrin receptors, many of which have been implicated in cancer. Although the IRS proteins share significant homology, distinct functions have...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789198/ https://ncbi.nlm.nih.gov/pubmed/19920186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1152 |
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