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IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers

Previous studies have postulated an important role for the inwardly rectifying potassium current (I(K1)) in controlling the dynamics of electrophysiological spiral waves responsible for ventricular tachycardia and fibrillation. In this study, we developed a novel tissue model of cultured neonatal ra...

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Detalhes bibliográficos
Main Authors: Sekar, Rajesh B., Kizana, Eddy, Cho, Hee C., Molitoris, Jared M., Hesketh, Geoffrey G., Eaton, Brett P., Marbán, Eduardo, Tung, Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789171/
https://ncbi.nlm.nih.gov/pubmed/19122180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.178335
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