Time-dependent Autoinactivation of Phospho-Thr(286)-αCa(2+)/Calmodulin-dependent Protein Kinase II

Ca(2+)/calmodulin-dependent protein kinase II (αCaMKII) is thought to exert its role in memory formation by autonomous Ca(2+)-independent persistent activity conferred by Thr(286) autophosphorylation, allowing the enzyme to remain active even when intracellular [Ca(2+)] has returned to resting level...

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Bibliographische Detailangaben
Hauptverfasser: Jama, Abdirahman M., Fenton, Jon, Robertson, Saralili D., Török, Katalin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Enzyme Catalysis and Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788865/
https://ncbi.nlm.nih.gov/pubmed/19654320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005900
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