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Role of Isoprenylcysteine Carboxylmethyltransferase-catalyzed Methylation in Rho Function and Migration

A number of proteins that play key roles in biological regulatory events undergo a process of post-translational modifications termed prenylation. The prenylation pathway consists of three enzymatic steps; the final processed protein is isoprenoid-modified and methylated on the C-terminal cysteine....

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Bibliografiske detaljer
Main Authors: Cushman, Ian, Casey, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788848/
https://ncbi.nlm.nih.gov/pubmed/19651782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025296
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