N(α)-Tosyl-l-phenylalanine Chloromethyl Ketone Induces Caspase-dependent Apoptosis in Transformed Human B Cell Lines with Transcriptional Down-regulation of Anti-apoptotic HS1-associated Protein X-1

N(α)-Tosyl-l-phenylalanine chloromethylketone (TPCK) has been widely used to investigate signal transduction pathways that are involved in gene expression and cell survival/cell death. However, contradictory effects of TPCK on apoptosis have been reported, and the underlying signaling events leading...

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Библиографические подробности
Главные авторы: Jitkaew, Siriporn, Trebinska, Alicja, Grzybowska, Ewa, Carlsson, Göran, Nordström, Anders, Lehtiö, Janne, Fröjmark, Anne-Sophie, Dahl, Niklas, Fadeel, Bengt
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Mechanisms of Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788833/
https://ncbi.nlm.nih.gov/pubmed/19679660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027912
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