The Inhibition of TREK2 Channel by an Oxidizing Agent, 5,5'-dithio-bis (2-nitrobenzoic acid), via Interaction with the C-terminus Distal to the 353rd Amino Acid

TREK (TWIK-RElated K(+) channels) and TRAAK (TWIK-Related Arachidonic acid Activated K(+) channels) were expressed in COS-7 cells, and the channel activities were recorded from inside-out membrane patches using holding potential of -40 mV in symmetrical 150 mM K(+) solution. Intracellular applicatio...

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Hlavní autoři: Park, Kyoung Sun, Bang, Hyoweon, Shin, Eun-Young, Kim, Chan Hyung, Kim, Yangmi
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2008
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788638/
https://ncbi.nlm.nih.gov/pubmed/19967058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2008.12.4.211
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