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DISPARE: DIScriminative PAttern REfinement for Position Weight Matrices

BACKGROUND: The accurate determination of transcription factor binding affinities is an important problem in biology and key to understanding the gene regulation process. Position weight matrices are commonly used to represent the binding properties of transcription factor binding sites but suffer f...

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Bibliografiske detaljer
Main Authors: da Piedade, Isabelle, Tang, Man-Hung Eric, Elemento, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788558/
https://ncbi.nlm.nih.gov/pubmed/19941641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-388
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